Description

1-Propanone, 2-Amino-1-(2-Fluorophenyl)- is a specialized fluorinated amino ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino and a fluorophenyl group, makes it a valuable precursor for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of new chemical entities, particularly for central nervous system (CNS) and other therapeutic targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• CNS Drug Development: Serves as a building block for compounds targeting neurological and psychiatric disorders.
• Fluorinated Compound Synthesis: Essential for introducing the 2-fluorophenyl moiety into more complex molecular architectures.
• Chemical Biology Probes: Can be utilized in the synthesis of probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-Propanone, 2-Amino-1-(2-Fluorophenyl)-
CAS No.	726123-51-9
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	2-Amino-1-(2-fluorophenyl)propan-1-one; 1-(2-Fluorophenyl)-2-aminopropan-1-one; 2-Amino-1-(2-fluorophenyl)propanone; α-Aminopropiophenone, 2'-fluoro-; 2'-Fluoro-α-aminopropiophenone; 2-Fluoro-α-aminopropiophenone; FAPP
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our advanced intermediates. Each batch of 1-Propanone, 2-Amino-1-(2-Fluorophenyl)- is analyzed to ensure high chemical purity and consistency, critical for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. Our quality system supports development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and acids. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.