Description

2''-Methyl-5''-(Trifluoromethyl)Acetophenone CAS NO 725743-50-0 is a high-value fluorinated aromatic ketone intermediate. This compound is critical for its role in synthesizing advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of a trifluoromethyl group can dramatically alter biological activity and metabolic stability. It is primarily sought after by research institutions and industrial manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require fluorinated aromatic units for specific thermal or optical properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for developing new synthetic methodologies and as a ligand or substrate in catalytic reactions.
• Fine Chemical Production: Utilized in the manufacture of complex fluorinated fine chemicals and dyes.

Basic Information

Product Name	2''-Methyl-5''-(Trifluoromethyl)Acetophenone
CAS No.	725743-50-0
Molecular Formula	C10H9F3O
Molecular Weight	202.18 g/mol
Synonyms	1-[2-Methyl-5-(trifluoromethyl)phenyl]ethanone; 2-Methyl-5-(trifluoromethyl)acetophenone; 2'-Methyl-5'-(trifluoromethyl)acetophenone; 2-Methyl-α,α,α-trifluoro-m-acetophenone; m-Acetotoluidide, 3-(trifluoromethyl)-; Ethanone, 1-[2-methyl-5-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of 2''-Methyl-5''-(Trifluoromethyl)Acetophenone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We operate under a quality system designed to meet the rigorous standards required by our global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.