Description

2-(Dichloromethyl)-4(3H)-Quinazolinone is a specialized heterocyclic organic compound that serves as a versatile and valuable synthetic intermediate. Its core quinazolinone scaffold, functionalized with a reactive dichloromethyl group, makes it a critical building block for constructing more complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in research laboratories for constructing complex quinazolinone derivatives and fused heterocyclic systems for material science and chemical biology studies.
• Chemical Research & Development: Serves as a standard or reference compound in methodological studies for new chlorination or cyclization reactions.
• Fine Chemical Production: Utilized in the scaled-up manufacture of specialty chemicals used in dyes, pigments, and advanced materials.

Basic Information

Product Name	2-(Dichloromethyl)-4(3H)-Quinazolinone
CAS No.	724746-72-9
Molecular Formula	C9H6Cl2N2O
Molecular Weight	229.06 g/mol
Synonyms	2-(Dichloromethyl)-4-hydroxyquinazoline; 4(3H)-Quinazolinone, 2-(dichloromethyl)-; 2-(Dichloromethyl)quinazolin-4(3H)-one; Quinazolin-4(3H)-one, 2-(dichloromethyl)-; 724746-72-9; 2-Dichloromethyl-4-quinazolinone
EINECS	Contact for details

Quality Control

Our 2-(Dichloromethyl)-4(3H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.