Description

2,2,2-Trifluoro-1-Furan-3-Yl-Ethanol is a high-value fluorinated building block characterized by its unique trifluoroethanol moiety attached to a furan heterocycle. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where the introduction of fluorine atoms is known to enhance metabolic stability, bioavailability, and binding affinity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for their unique electronic and surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	2,2,2-Trifluoro-1-Furan-3-Yl-Ethanol
CAS No.	722491-62-5
Molecular Formula	C6H5F3O2
Molecular Weight	166.10 g/mol
Synonyms	3-(2,2,2-Trifluoro-1-hydroxyethyl)furan; 1-(3-Furyl)-2,2,2-trifluoroethanol; 2,2,2-Trifluoro-1-(3-furyl)ethanol; α-(Trifluoromethyl)-3-furanmethanol; 3-Furyl(trifluoromethyl)carbinol; 2,2,2-Trifluoro-1-(furan-3-yl)ethanol
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-Furan-3-Yl-Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.