Description

5'-Chloro-2(2',4'-Dichlorophenyl)-2'-Hydroxy-4'-Methyl Acetophenone is a specialized chlorinated acetophenone derivative with a complex phenolic structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its precise molecular architecture makes it a valuable building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors where specific halogenation patterns are required. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in antimicrobial and anti-inflammatory therapeutic classes.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its chlorinated phenyl groups.
• Organic Synthesis Building Block: Used in cross-coupling reactions, cyclizations, and other transformations to introduce specific halogenated and hydroxylated motifs.
• Material Science Research: Potential intermediate for synthesizing specialty polymers, ligands for catalysis, or organic electronic materials.
• Chemical Reference Standard: Utilized in analytical laboratories for method development, calibration, and quality control testing.

Basic Information

Product Name	5'-Chloro-2(2',4'-Dichlorophenyl)-2'-Hydroxy-4'-Methyl Acetophenone
CAS No.	720676-78-8
Molecular Formula	C15H11Cl3O2
Molecular Weight	329.60 g/mol
Synonyms	2'-Hydroxy-5'-chloro-2,4'-dichloro-4-methylacetophenone; 1-(5-Chloro-2-hydroxyphenyl)-2-(2,4-dichlorophenyl)-1-propanone; 5'-Chloro-2,4'-dichloro-2'-hydroxy-4-methylacetophenone; 2,4-Dichloro-α-(5-chloro-2-hydroxyphenyl)-o-methylacetophenone; CAS 720676-78-8; 5'-Chloro-2(2',4'-dichlorophenyl)-2'-hydroxy-4'-methylacetophenone
EINECS	Contact for details

Quality Control

Our 5'-Chloro-2(2',4'-Dichlorophenyl)-2'-Hydroxy-4'-Methyl Acetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.