Description

4-Chloro-2-([4-(Trifluoromethoxy)Anilino]Methyl)Benzenol is a specialized organic compound featuring a trifluoromethoxy-substituted aniline moiety, a structure of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique fluorinated properties into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for advanced electronic materials, contributing to the molecular framework of dyes, pigments, and charge-transport layers.
• Organic Ligand Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs) in academic and industrial research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	4-Chloro-2-([4-(Trifluoromethoxy)Anilino]Methyl)Benzenol
CAS No.	720667-84-5
Molecular Formula	C14H11ClF3NO2
Molecular Weight	317.69 g/mol
Synonyms	4-Chloro-2-[(4-trifluoromethoxyanilino)methyl]phenol; 2-[(4-Trifluoromethoxyphenylamino)methyl]-4-chlorophenol; 4-Chloro-2-({[4-(trifluoromethoxy)phenyl]amino}methyl)phenol; Benzenol, 4-chloro-2-[[[4-(trifluoromethoxy)phenyl]amino]methyl]-; CAS 720667-84-5
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-([4-(Trifluoromethoxy)Anilino]Methyl)Benzenol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP compliance for pharmaceutical applications and can accommodate specific customer requirements for custom grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.