Description

3-Fluoro-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-couplings for synthesizing novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates.
• Agrochemical Synthesis: Used to create advanced, fluorinated pyridine-based herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Material Science Research: Serves as a precursor for organic electronic materials, such as those used in OLEDs and organic semiconductors, where the fluorine and boronic ester functionalities tune electronic properties.
• Chemical Biology & Probe Design: Utilized in the synthesis of molecular probes and bio-conjugates for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Fluoro-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine
CAS No.	719268-92-5
Molecular Formula	C11H15BFNO2
Molecular Weight	223.05 g/mol
Synonyms	3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-fluoropyridine; 3-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Fluoro-5-pyridineboronic acid pinacol ester; (3-Fluoropyridin-5-yl)boronic acid pinacol ester; 3-Fluoro-5-(pinacolboranyl)pyridine; 719268-92-5; 3-Fluoro-5-pyridylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive cross-coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.