Description

2-Amino-5-(Trifluoromethyl)Oxazole is a high-value, multi-functional heterocyclic building block characterized by its unique oxazole core and trifluoromethyl group. This compound is essential for synthetic chemists seeking to incorporate fluorine and nitrogen-containing motifs into target molecules, which can dramatically alter their physicochemical and biological properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-infectives, and CNS-active compounds.
• Agrochemical Synthesis: Serves as a critical building block in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials that require specific heterocyclic architectures.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or labeling agent in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for use in bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Amino-5-(Trifluoromethyl)Oxazole
CAS No.	714972-00-6
Molecular Formula	C4H3F3N2O
Molecular Weight	152.08 g/mol
Synonyms	5-(Trifluoromethyl)-1,3-oxazol-2-amine; 2-Amino-5-(trifluoromethyl)-1,3-oxazole; 5-(Trifluoromethyl)oxazol-2-amine; 2-Amino-5-trifluoromethyloxazole; 714972-00-6; 2-Amino-5-(trifluoromethyl)oxazole; Oxazole, 2-amino-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-(Trifluoromethyl)Oxazole is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.