Description

5-Azidomethyl-2-Hydroxybenzaldehyde is a versatile bifunctional organic building block containing both an aldehyde and a photoreactive azide group. This compound matters for its unique reactivity, enabling its use as a key intermediate in click chemistry, bioconjugation, and the synthesis of complex molecular architectures. It is primarily needed by researchers and manufacturers in pharmaceutical development, materials science, and chemical biology for creating probes, polymers, and advanced drug delivery systems.

Application

• Bioconjugation & Probe Synthesis: Acts as a photoreactive crosslinker for labeling biomolecules (proteins, peptides, nucleic acids) via Staudinger-Bertozzi ligation or copper-free click chemistry.
• Pharmaceutical Intermediates: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and targeted therapeutics.
• Polymer & Materials Science: Used to functionalize polymer backbones and surfaces, introducing aldehyde handles for further modification to create smart materials and hydrogels.
• Chemical Biology Tools: Employed in the development of activity-based probes (ABPs) and photoaffinity labels for studying enzyme function and protein interactions.
• Ligand & Catalyst Development: Provides a scaffold for constructing chelating ligands and organocatalysts with specific binding sites.
• Surface Immobilization: Facilitates the covalent attachment of molecules to surfaces (e.g., chips, nanoparticles) for biosensor and diagnostic device fabrication.

Basic Information

Product Name	5-Azidomethyl-2-Hydroxybenzaldehyde
CAS No.	714916-55-9
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	2-Hydroxy-5-(azidomethyl)benzaldehyde; 5-(Azidomethyl)salicylaldehyde; Salicylaldehyde, 5-(azidomethyl)-; 5-Azidomethylsalicylaldehyde; Azidomethyl Hydroxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Azidomethyl-2-Hydroxybenzaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.