Description

1-(3,4-Dichloro-Benzyl)-1H-Pyrrole-2-Carbaldehyde is a high-purity, functionalized pyrrole derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a pyrrole-2-carbaldehyde core with a 3,4-dichlorobenzyl substituent, enabling precise chemical modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Serves as a precursor in the synthesis of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrrole moiety.
• Organic Synthesis Building Block: Used in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, and as a substrate for constructing complex nitrogen-containing heterocycles.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-(3,4-Dichloro-Benzyl)-1H-Pyrrole-2-Carbaldehyde
CAS No.	714278-18-9
Molecular Formula	C12H9Cl2NO
Molecular Weight	254.11 g/mol
Synonyms	1-[(3,4-Dichlorophenyl)methyl]-1H-pyrrole-2-carboxaldehyde; 1-(3,4-Dichlorobenzyl)pyrrole-2-carbaldehyde; 1H-Pyrrole-2-carboxaldehyde, 1-[(3,4-dichlorophenyl)methyl]-; 714278-18-9; 1-(3,4-Dichlorobenzyl)-1H-pyrrole-2-carboxaldehyde; Pyrrole-2-carboxaldehyde, 1-(3,4-dichlorobenzyl)-; 1-(3,4-Dichloro-benzyl)-1H-pyrrol-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dichloro-Benzyl)-1H-Pyrrole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.