Description

(E)-11-Bromomethylene-3,8-Difluoro-6,11-Dihydro-Dibenzo[B,E]Oxepine CAS NO 710349-01-2 is a high-purity, advanced pharmaceutical intermediate characterized by its unique oxepine ring structure and halogen substituents. This compound is critical for enabling complex synthetic pathways in modern medicinal chemistry, offering a precise building block for targeted molecular construction. It is primarily required by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging its difluoro and bromomethylene functional groups.
• Material Science Research: Serves as a monomer or specialty additive in the development of novel polymers and organic electronic materials.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for constructing complex heterocyclic frameworks.
• Ligand and Catalyst Development: Utilized as a scaffold for creating specialized ligands in transition metal catalysis.

Basic Information

Product Name	(E)-11-Bromomethylene-3,8-Difluoro-6,11-Dihydro-Dibenzo[B,E]Oxepine
CAS No.	710349-01-2
Molecular Formula	C15H9BrF2O
Molecular Weight	335.14 g/mol
Synonyms	11-Bromomethylene-3,8-difluoro-6,11-dihydrodibenzo[b,e]oxepine; (E)-11-(Bromomethylene)-3,8-difluoro-6,11-dihydrodibenzo[b,e]oxepine; Dibenzo[b,e]oxepine, 6,11-dihydro-11-(bromomethylene)-3,8-difluoro-, (E)-; 710349-01-2; (E)-11-Bromomethylene-3,8-difluoro-6,11-dihydrodibenzo[b,e]oxepine; Bromomethylene-difluoro-dihydrodibenzooxepine
EINECS	Contact for details

Quality Control

Our (E)-11-Bromomethylene-3,8-Difluoro-6,11-Dihydro-Dibenzo[B,E]Oxepine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.