Description

3-Fluoro-5-Nitrobenzeneboronic Acid Pinacol Ester, 96% is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and nitro-substituted aromatic systems.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides where the specific substitution pattern can influence bioactivity.
• Materials Science Research: A precursor for synthesizing organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Useful in the development of molecular probes and sensors due to the reactivity of the boronic ester group and the spectroscopic handles provided by fluorine and nitro groups.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific, high-value boronic acid derivatives.

Basic Information

Product Name	3-Fluoro-5-Nitrobenzeneboronic Acid Pinacol Ester, 96%
CAS No.	710348-94-0
Molecular Formula	C12H15BFNO4
Molecular Weight	267.06 g/mol
Synonyms	3-Fluoro-5-nitrobenzeneboronic acid pinacol ester; 5-Nitro-3-fluorobenzeneboronic acid pinacol ester; (3-Fluoro-5-nitrophenyl)boronic acid pinacol ester; 2-(3-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Fluoro-5-nitrophenylboronic acid pinacol ester; B-(3-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; PINACOL 3-FLUORO-5-NITROBENZENEBORONATE
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-Nitrobenzeneboronic Acid Pinacol Ester undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (HPLC/GC), identity (NMR, IR), and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.