Description

2-Oxo-2,3-Dihydro-1H-Benzoimidazole-5-Boronic Acid, Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and key building block in modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with improved efficacy and environmental profiles.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Research: A versatile reagent in academic and industrial R&D for constructing benzimidazole-derived libraries via palladium-catalyzed cross-coupling.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Bioconjugation: Potential use in the development of bioconjugates and probe molecules for diagnostic applications.

Basic Information

Product Name	2-Oxo-2,3-Dihydro-1H-Benzoimidazole-5-Boronic Acid, Pinacol Ester
CAS No.	710348-69-9
Molecular Formula	C₁₃H₁₅BN₂O₃
Molecular Weight	258.08 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-benzimidazol-2-one; 2-Oxo-2,3-dihydro-1H-benzo[d]imidazole-5-boronic acid pinacol ester; 1,3-Dihydro-2H-benzimidazol-2-one, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Benzimidazolone-5-boronic acid pinacol ester; 5-Borono-2-benzimidazolinone pinacol ester; 710348-69-9; 2-Oxobenzimidazoline-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3-Dihydro-1H-Benzoimidazole-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee consistent quality and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.