Description

1,3-Dioxolane, 2,2-Dimethyl-4-(1-Propynyl)-, (4R)- (9Ci) is a specialized chiral building block and protected aldehyde derivative of significant interest in advanced organic synthesis. Its value lies in its unique stereochemistry and functional group compatibility, enabling the precise construction of complex molecular architectures. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where high purity and defined stereochemistry are critical.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research.
• Material Science: Potential monomer or precursor for synthesizing novel polymers with specific optical or material properties.

Basic Information

Product Name	1,3-Dioxolane, 2,2-Dimethyl-4-(1-Propynyl)-, (4R)- (9Ci)
CAS No.	710324-25-7
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	(4R)-2,2-Dimethyl-4-(prop-1-yn-1-yl)-1,3-dioxolane; (R)-2,2-Dimethyl-4-(1-propynyl)-1,3-dioxolane; (R)-4-(1-Propynyl)-2,2-dimethyl-1,3-dioxolane; (R)-Acetaldehyde Propynyl Acetal; (R)-Propynyl Acetal of Acetaldehyde; (R)-2,2-Dimethyl-4-(prop-2-yn-1-yl)-1,3-dioxolane (tautomer); Chiral Dioxolane Propynyl Derivative
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane, 2,2-Dimethyl-4-(1-Propynyl)-, (4R)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC or GC, to meet the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 98.0%
Water Content (KF Titration)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.