Description

Methyl4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate is a high-purity, versatile organoboron building block essential for modern synthetic chemistry. This compound is a critical intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex thiophene-containing molecules. It is primarily used by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing thiophene or biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Organic Electronics: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Material Science Research: Enables the creation of complex organic frameworks and functional materials with tailored properties.
• Chemical Biology & Medicinal Chemistry: Facilitates the synthesis of molecular probes and drug candidates for biological screening and target identification.
• Catalyst & Ligand Development: Used to prepare novel boron-containing ligands for transition metal catalysis.

Basic Information

Product Name	Methyl4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate
CAS No.	709648-80-6
Molecular Formula	C12H17BO4S
Molecular Weight	268.14 g/mol
Synonyms	Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Methyl 4-(pinacolatoboran-2-yl)thiophene-2-carboxylate; 4-(Pinacolatoboryl)thiophene-2-carboxylic acid methyl ester; Methyl 4-(pinacolatoboryl)thiophene-2-carboxylate; 709648-80-6; Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thiophenecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.