Description

1-(4-Bromo-2-Methylphenyl)Propan-1-One is a high-purity organic building block and key intermediate in advanced chemical synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromo and ketone functional groups enable further derivatization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional organic materials due to its aromatic core and substituents.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Industrial R&D: Utilized in research laboratories for methodological studies in cross-coupling reactions and ketone chemistry.

Basic Information

Product Name	1-(4-Bromo-2-Methylphenyl)Propan-1-One
CAS No.	709025-22-9
Molecular Formula	C10H11BrO
Molecular Weight	227.10 g/mol
Synonyms	1-(4-Bromo-2-methylphenyl)-1-propanone; 4'-Bromo-2'-methylpropiophenone; Propiophenone, 4'-bromo-2'-methyl-; 1-Propanone, 1-(4-bromo-2-methylphenyl)-; 4-Bromo-2-methylpropiophenone; 2-Methyl-4-bromopropiophenone; p-Bromo-o-methylpropiophenone; (4-Bromo-2-methylphenyl) ethyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-2-Methylphenyl)Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.