Description

(R)-1-(tert-Butoxycarbonyl)-2-Propylpyrrolidine-2-Carboxylic Acid is a high-purity chiral building block and advanced pharmaceutical intermediate of significant commercial importance. This compound is valued for its role in the synthesis of complex, biologically active molecules, particularly in the development of new therapeutic agents. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in asymmetric synthesis and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Serves as a crucial building block for constructing complex molecules with defined stereochemistry, essential for modern medicinal chemistry.
• Peptidomimetics & Proline Derivatives: Used in the synthesis of peptidomimetic compounds and modified proline analogs for drug discovery programs.
• Catalyst & Ligand Development: Acts as a precursor for developing novel chiral catalysts and ligands used in enantioselective transformations.
• Academic & Industrial Research: Employed in chemical research for studying reaction mechanisms and developing new synthetic methodologies.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and bespoke intermediates for the life sciences industry.

Basic Information

Product Name	(R)-1-(tert-Butoxycarbonyl)-2-Propylpyrrolidine-2-Carboxylic Acid
CAS No.	706806-57-7
Molecular Formula	C13H23NO4
Molecular Weight	257.33 g/mol
Synonyms	(R)-1-Boc-2-Propylpyrrolidine-2-carboxylic Acid; (R)-1-(tert-Butoxycarbonyl)-2-propylpyrrolidine-2-carboxylic Acid; (R)-2-Propyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic Acid; (R)-1-N-Boc-2-propylproline; (R)-1-Boc-2-propylproline; (2R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-2-propylpyrrolidine-2-carboxylic Acid; (R)-1-(Boc)-2-propylproline; 706806-57-7
EINECS	Contact for details

Quality Control

Our (R)-1-(tert-Butoxycarbonyl)-2-Propylpyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.