Description

(1R)-2'-(Bromomethyl)-[1,1'-Binaphthalene]-2-Carboxaldehyde is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is a critical synthon in asymmetric synthesis, valued for its ability to impart axial chirality and serve as a precursor to complex ligands and catalysts. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and specialty materials.

Application

• Asymmetric Catalyst Synthesis: A key precursor for constructing BINOL and BINAP-type chiral ligands and organocatalysts.
• Pharmaceutical Intermediate: Used in the research and development of chiral drug candidates, particularly in oncology and CNS therapeutic areas.
• Material Science Research: Serves as a building block for chiral organic frameworks (COFs) and advanced functional materials.
• Agrochemical Development: Employed in the synthesis of enantiomerically pure pesticides and herbicides.
• Academic & Process Chemistry: A valuable reagent for methodological studies in stereoselective C-C and C-X bond formation.

Basic Information

Product Name	(1R)-2'-(Bromomethyl)-[1,1'-Binaphthalene]-2-Carboxaldehyde
CAS No.	705931-79-9
Molecular Formula	C23H15BrO
Molecular Weight	387.27 g/mol
Synonyms	(R)-2'-(Bromomethyl)-[1,1'-binaphthalene]-2-carboxaldehyde; (1R)-2'-(Bromomethyl)-1,1'-binaphthyl-2-carboxaldehyde; (R)-2'-(Bromomethyl)-1,1'-binaphthyl-2-carboxaldehyde; (R)-BINOL-Br-CHO; (R)-2-Formyl-6'-(bromomethyl)-1,1'-binaphthyl; (1R)-2'-(Bromomethyl)-1,1'-binaphthalene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our (1R)-2'-(Bromomethyl)-[1,1'-Binaphthalene]-2-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with research and production-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.