Description

Mandelonitrile, 2-Methoxy-4-Methyl- (5Ci) is a specialized organic nitrile derivative, serving as a crucial chiral building block and intermediate in advanced chemical synthesis. Its value lies in its unique molecular structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This high-purity intermediate is essential for R&D chemists and process development scientists working on novel active ingredients, particularly in the fine chemical and life science sectors. The compound is supplied with full traceability and analytical documentation to support critical development workflows.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides with specific stereochemistry.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to introduce the mandelonitrile moiety into more complex molecular architectures.
• Asymmetric Catalysis Studies: Serves as a substrate or ligand precursor in the development of new catalytic systems.
• Flavor & Fragrance Chemistry: Intermediate for the synthesis of complex aroma chemicals.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	Mandelonitrile, 2-Methoxy-4-Methyl- (5Ci)
CAS No.	705288-16-0
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	2-Methoxy-4-methylmandelonitrile; (RS)-2-Methoxy-4-methylmandelonitrile; α-Hydroxy-2-methoxy-4-methylbenzeneacetonitrile; 2-(2-Methoxy-4-methylphenyl)-2-hydroxyacetonitrile; 2-Methoxy-4-methylbenzaldehyde cyanohydrin; 4-Methyl-2-methoxymandelonitrile; (2-Methoxy-4-methylphenyl)(hydroxy)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of Mandelonitrile, 2-Methoxy-4-Methyl- (5Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure full traceability and support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the nitrile functional group, ensure proper segregation from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.