Description

Propanedioic Acid, 2-[(2E)-3-Chloro-2-Propen-1-Yl]-2-(1-Methylethyl)-, 1,3-Dimethyl Ester is a specialized synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring a propanedioate core with chloroalkenyl and isopropyl substituents, which provides a versatile scaffold for constructing complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those requiring complex ester and alkene functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its chlorinated alkene group can be leveraged for further chemical modifications.
• Organic Synthesis Reagent: Acts as a versatile Michael acceptor or alkylating agent in academic and industrial research laboratories for constructing carbon-carbon bonds.
• Material Science Research: Investigated as a potential monomer or cross-linking agent for the development of specialized polymers with unique properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or biological pathways due to its reactive handles.

Basic Information

Item	Detail
Product Name	Propanedioic Acid, 2-[(2E)-3-Chloro-2-Propen-1-Yl]-2-(1-Methylethyl)-, 1,3-Dimethyl Ester
CAS No.	705259-97-8
Molecular Formula	C12H19ClO4
Molecular Weight	262.73 g/mol
Synonyms	Dimethyl 2-(3-chloroallyl)-2-isopropylmalonate; 2-(3-Chloro-2-propen-1-yl)-2-(1-methylethyl)-1,3-propanedioic acid dimethyl ester; Isopropyl 3-chloroallylmalonate dimethyl ester; (2E)-3-Chloro-2-propen-1-yl isopropyl malonate dimethyl ester; Propanedioic acid, 2-(3-chloro-2-propenyl)-2-(1-methylethyl)-, dimethyl ester; 2-Isopropyl-2-(3-chloroallyl)malonic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our Propanedioic Acid, 2-[(2E)-3-Chloro-2-Propen-1-Yl]-2-(1-Methylethyl)-, 1,3-Dimethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with full traceability are provided for all shipments, supporting compliance with cGMP and research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.