Description

1H-Cyclopenta[C]Furan-5(3H)-One,Tetrahydro-4-(2-Methyl-1-Methylenepropyl)-,(3Ar,4R,6Ar)-Rel-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined bicyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), where its specific stereochemistry is essential for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on new drug candidates, particularly in therapeutic areas requiring sophisticated molecular scaffolds. The product is supplied under strict quality control, with CAS number 704907-60-8.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug molecules, particularly for central nervous system (CNS) or anti-inflammatory targets.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in the development of new catalytic systems due to its rigid, three-dimensional structure.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthesizing novel odorants and flavoring agents with unique organoleptic properties derived from its fused ring system.
• Agrochemical Development: Employed in research for creating new generation pesticides or herbicides where the cyclopentafuranone core provides bioactivity.
• Material Science Research: Investigated as a monomer or building block for specialty polymers with specific optical or mechanical characteristics.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in organic synthesis and natural product analog creation.

Basic Information

Item	Detail
Product Name	1H-Cyclopenta[C]Furan-5(3H)-One,Tetrahydro-4-(2-Methyl-1-Methylenepropyl)-,(3Ar,4R,6Ar)-Rel-(9Ci)
CAS No.	704907-60-8
Molecular Formula	C12H18O2
Molecular Weight	194.27 g/mol
Synonyms	(3aR,4R,6aR)-Tetrahydro-4-(2-methyl-1-methylenepropyl)-1H-cyclopenta[c]furan-5(3H)-one; rel-(3aR,4R,6aR)-Tetrahydro-4-(2-methylprop-1-en-2-yl)-1H-cyclopenta[c]furan-5(3H)-one; Tetrahydro-4-(2-methyl-1-methylenepropyl)-1H-cyclopenta[c]furan-5(3H)-one, (3aR,4R,6aR)-rel-; Bicyclic furanone derivative; Chiral cyclopentafuranone intermediate.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict cGMP (current Good Manufacturing Practice) guidelines to ensure traceability and reproducibility. Our quality commitment includes comprehensive analytical characterization using HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support regulatory filings with stability data and can tailor specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend keeping the material at 2-8°C under an inert atmosphere to maintain optimal stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.