Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 7-Hydroxy-, (1R,2R,4R,7R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block and synthetic intermediate. Its value lies in its rigid, functionalized norbornene-like structure, which is essential for constructing complex molecules with precise three-dimensional architecture. This advanced intermediate is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for applications in asymmetric catalysis, medicinal chemistry, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in areas requiring rigid, polycyclic scaffolds.
• Asymmetric Synthesis: Employed as a precursor or ligand in catalytic asymmetric reactions to induce high enantioselectivity.
• Medicinal Chemistry: Used to explore structure-activity relationships (SAR) by introducing a constrained, functionalized bicyclic system into lead compounds.
• Fine Chemical Production: Serves as a building block for synthesizing specialty chemicals, flavors, fragrances, and advanced materials.
• Academic & Industrial Research: A valuable tool for chemists studying cycloaddition reactions, ring-opening metathesis polymerization (ROMP) precursors, and novel molecular architectures.
• Process Chemistry Development: Used in scaling up synthetic routes for complex molecules where stereochemical control is paramount.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 7-Hydroxy-, (1R,2R,4R,7R)-Rel- (9Ci)
CAS No.	703400-29-7
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	(1R,2R,4R,7R)-7-Hydroxybicyclo[2.2.1]hept-5-ene-2-carboxylic Acid; rel-(1R,2R,4R,7R)-7-Hydroxybicyclo[2.2.1]hept-5-ene-2-carboxylic Acid; 7-Hydroxynorborn-5-ene-2-carboxylic Acid (stereospecific); Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 7-hydroxy-, (1R,2R,4R,7R)-rel-; Norbornene derivative carboxylic acid.
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 7-Hydroxy-, (1R,2R,4R,7R)-Rel- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity and compliance with customer specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.