Description

Cyclobutanecarboxaldehyde, 2-[(Acetyloxy)Methyl]-, (1R,2S)- (9Ci) is a high-purity, chiral cyclobutane derivative that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique stereochemistry and functional groups, enabling the construction of complex molecular architectures with precise spatial orientation. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the cyclobutane ring contributes to unique biological activity.
• Asymmetric Catalysis Research: Employed as a sophisticated substrate or ligand precursor in the development of new asymmetric catalytic reactions.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers with tailored thermal or mechanical properties.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, high-value aroma chemicals due to its constrained cyclic structure.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, total synthesis projects, and exploring new reaction mechanisms.

Basic Information

Product Name	Cyclobutanecarboxaldehyde, 2-[(Acetyloxy)Methyl]-, (1R,2S)- (9Ci)
CAS No.	701292-25-3
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(1R,2S)-2-[(Acetyloxy)methyl]cyclobutanecarboxaldehyde; (1R,2S)-2-(Acetoxymethyl)cyclobutanecarbaldehyde; (1R,2S)-2-(Acetoxymethyl)cyclobutanecarboxaldehyde; (1R,2S)-rel-2-[(Acetyloxy)methyl]cyclobutanecarboxaldehyde; Cyclobutanecarboxaldehyde, 2-[(acetyloxy)methyl]-, (1R,2S)-; (1R,2S)-2-(Hydroxymethyl)cyclobutanecarboxaldehyde acetate
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxaldehyde, 2-[(Acetyloxy)Methyl]-, (1R,2S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive; allow the sealed container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.