Description

Neopentylboronic Acid is a specialized organoboron compound featuring a sterically hindered neopentyl group attached to a boronic acid functionality. This structural feature makes it a valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions that require high selectivity and stability. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs) and agrochemical intermediates.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, especially where the neopentyl group is required to modulate pharmacokinetic properties.
• Agrochemical Product Development: Employed in creating new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Material Science Research: Applied in the development of organic electronic materials, polymers, and liquid crystals.
• Chemical Biology and Bioconjugation: Utilized in probe and linker synthesis for studying biological systems.

Basic Information

Product Name	Neopentylboronic Acid
CAS No.	701261-35-0
Molecular Formula	C5H13BO2
Molecular Weight	115.97 g/mol
Synonyms	Neopentylboronic Acid; (2,2-Dimethylpropyl)boronic Acid; 2,2-Dimethylpropylboronic Acid; Neopentyl-Boronic Acid; B-(2,2-Dimethylpropyl)boronic Acid; (Neopentyl)boronic Acid; Boronic acid, B-(2,2-dimethylpropyl)-
EINECS	Contact for details

Quality Control

Our Neopentylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for research and development in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.