Description

3'',5''-Dibromo-2,2,3,3,4,4,4-Heptafluorobutyrophenone is a specialized fluorinated and brominated aromatic ketone building block. This compound is valued for its unique combination of halogen substituents, which impart significant electronic and steric properties, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated and brominated motifs for enhanced bioavailability or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the heptafluorobutyl and dibromo groups can contribute to product efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials due to its ability to modify electronic properties and intermolecular interactions.
• Cross-Coupling Reactions: The bromine atoms make it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create more complex biaryl structures.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands or organocatalysts where the electron-withdrawing fluorinated chain can tune metal center reactivity or catalyst performance.

Basic Information

Product Name	3'',5''-Dibromo-2,2,3,3,4,4,4-Heptafluorobutyrophenone
CAS No.	79851-20-0
Molecular Formula	C10H3Br2F7O
Molecular Weight	423.93 g/mol
Synonyms	1-(3,5-Dibromophenyl)-2,2,3,3,4,4,4-heptafluorobutan-1-one; 3,5-Dibromo-2,2,3,3,4,4,4-heptafluorobutyrophenone; Heptafluorobutyryl-3,5-dibromobenzene; α,α,β,β,γ,γ,γ-Heptafluoro-3,5-dibromobutyrophenone; 3,5-Dibromoperfluorobutyrophenone
EINECS	Contact for details

Quality Control

Our 3'',5''-Dibromo-2,2,3,3,4,4,4-Heptafluorobutyrophenone is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and may be incompatible with strong bases and fluorides. Keep away from heat and ignition sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.