Description

2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetic Acid is a high-value boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its primary value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials synthesis. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-acetic acid motifs.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other functional polymers.
• Ligand & Catalyst Preparation: Utilized in the synthesis of specialized ligands for transition metal catalysis and organoboron reagents.
• Academic & Contract Research: A vital reagent for methodological development in synthetic organic chemistry laboratories worldwide.
• Peptide & Protein Modification: Employed in bioconjugation chemistry to introduce boron-containing handles for further functionalization.

Basic Information

Product Name	2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetic Acid
CAS No.	79775-05-6
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylacetic Acid; 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetic Acid; (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic Acid; 2-(3-(Pinacolatoboryl)phenyl)acetic Acid; m-(Carboxymethyl)phenylboronic Acid Pinacol Ester; B-[3-(Carboxymethyl)phenyl]boronic Acid Pinacol Ester; 79775-05-6
EINECS	Contact for details

Quality Control

Our 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for sensitive cross-coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.