Description

2,2-Difluoroethylamine Hydrochloride is a high-purity, organofluorine building block essential for advanced synthetic chemistry. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is key to modulating biological activity and metabolic stability. It is primarily sought after by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including protease inhibitors, kinase inhibitors, and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorination enhances efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating fluorinated ligands used in asymmetric catalysis and material science.
• Peptide Modification: Employed to introduce fluorine-containing functional groups into peptides and peptidomimetics for biochemical research.
• Fluorinated Polymer Research: Acts as a monomer or modifier in the development of specialty polymers with unique surface properties and chemical resistance.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biomolecules for studying metabolic pathways and protein interactions.

Basic Information

Product Name	2,2-Difluoroethylamine Hydrochloride
CAS No.	79667-91-7
Molecular Formula	C2H6ClF2N
Molecular Weight	117.52 g/mol
Synonyms	2,2-Difluoroethanamine Hydrochloride; 2,2-Difluoroethylammonium Chloride; 1-Amino-2,2-difluoroethane Hydrochloride; 2,2-Difluoro-1-aminoethane Hydrochloride; Ethanamine, 2,2-difluoro-, hydrochloride; 2,2-Difluoroethylamine HCl; 79667-91-7
EINECS	Contact for details

Quality Control

Our 2,2-Difluoroethylamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant cGMP guidelines for pharmaceutical intermediates, and our quality protocols are designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.