Description

3-(4-Chlorophenyl)-1,1,1-Trifluoro-2-Propanone is a high-value fluorinated aromatic ketone building block, recognized for its unique trifluoromethyl ketone moiety. This compound is essential for introducing the trifluoroacetyl group into molecular frameworks, a key step in developing compounds with enhanced metabolic stability and lipophilicity. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed in organic chemistry for the preparation of chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable reference compound and starting material for academic and industrial research into the properties and reactions of fluorinated organic molecules.

Basic Information

Product Name	3-(4-Chlorophenyl)-1,1,1-Trifluoro-2-Propanone
CAS No.	79611-55-5
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	1-(4-Chlorophenyl)-3,3,3-trifluoro-2-propanone; 4'-Chloro-3,3,3-trifluoropropiophenone; 4-Chlorophenyl trifluoroacetone; p-Chlorophenyl trifluoromethyl ketone; 3,3,3-Trifluoro-1-(4-chlorophenyl)propan-1-one; α,α,α-Trifluoro-4'-chloroacetophenone; CF3COCH2C6H4Cl
EINECS	Contact for details

Quality Control

Our production of 3-(4-Chlorophenyl)-1,1,1-Trifluoro-2-Propanone adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.