Description

Triptonolide CAS NO 79548-61-1 is a bioactive diterpenoid lactone compound isolated from the traditional medicinal plant *Tripterygium wilfordii* (Thunder God Vine). This compound is of significant interest for its potent biological activity, serving as a key reference standard and a promising scaffold for research into novel therapeutic agents. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and natural product sectors for drug discovery and pharmacological studies.

Application

• Pharmaceutical Research & Development: Serves as a high-purity reference standard for analytical method development, quality control, and pharmacokinetic studies.
• Bioactivity Screening: Used in in vitro and in vivo assays to investigate its anti-inflammatory, immunosuppressive, and potential anti-cancer properties.
• Natural Product Chemistry: A critical compound for the study and standardization of extracts derived from *Tripterygium wilfordii*.
• Lead Compound Optimization: Acts as a molecular scaffold for the semi-synthesis of analogs to explore structure-activity relationships (SAR) and improve therapeutic profiles.
• Academic & Institutional Research: Employed in university and government labs for fundamental research into diterpenoid biosynthesis and mechanism of action studies.

Basic Information

Product Name	Triptonolide
CAS No.	79548-61-1
Molecular Formula	C20H24O6
Molecular Weight	360.40 g/mol
Synonyms	Triptonolide; Triptonodiol; (1R,2S,4aS,6S,7R,8aS)-1,2,6,7-Tetrahydroxy-1,4a,6-trimethyl-7-[(2Z)-2-methylbut-2-enoyl]oxy-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene-2-carboxylic acid γ-lactone; Wilforlide A; Tripdiolide; Celastrol derivative; Triptolide analog
EINECS	Contact for details

Quality Control

Our Triptonolide is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for reference standards, and specifications can be aligned with client requirements for specific research or development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.