Description

(R)-4-Bromo-1,2-Epoxybutane CAS NO 79413-93-7 is a high-value, chiral epoxide building block essential for the synthesis of complex, optically active molecules. Its unique structure, featuring both a reactive epoxide ring and a bromine handle, makes it a versatile intermediate for introducing specific stereochemistry and functional groups. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of β-blockers, antiviral agents, and other therapeutic compounds requiring specific (R)-configuration.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where stereochemistry impacts biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical and Specialty Material Production: Employed in the manufacture of advanced polymers, liquid crystals, and other performance materials where optical purity is critical.
• Academic and Industrial R&D: A valuable tool in medicinal chemistry and process development for exploring new synthetic routes and creating compound libraries.

Basic Information

Product Name	(R)-4-Bromo-1,2-Epoxybutane
CAS No.	79413-93-7
Molecular Formula	C₄H₇BrO
Molecular Weight	151.00 g/mol
Synonyms	(R)-(-)-4-Bromo-1,2-epoxybutane; (R)-1-Bromo-3,4-epoxybutane; (2R)-2-[(2-Bromoethyl)oxirane]; (R)-4-Bromo-1,2-epoxybutane; (R)-4-Bromooxirane-2-ethanamine; (R)-4-Bromo-1,2-butylene oxide; (R)-4-Bromo-1,2-butylene oxide; (R)-4-Bromo-1,2-epoxybutane
EINECS	Contact for details

Quality Control

Our (R)-4-Bromo-1,2-Epoxybutane is produced under strict quality management protocols to ensure high chemical and optical purity for demanding synthetic applications. Each batch undergoes comprehensive analysis including chiral purity determination by chiral HPLC or GC, identity confirmation by IR and NMR spectroscopy, and assay by titration. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed and away from heat, sparks, and open flame. Keep separated from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee (R)
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.480 - 1.490
Density (g/mL at 20°C)	1.55 - 1.65

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.