Description

Ethyl 2,3,4,6-Tetra-O-acetyl-α-D-thiomannopyranoside (Contains Up To 20% Beta Isomer) is a high-purity, acetylated thioglycoside derivative of mannose, serving as a critical chiral building block and glycosyl donor in synthetic organic chemistry. This compound is valued for its role in the stereoselective synthesis of complex oligosaccharides, glycoconjugates, and novel therapeutic agents. It is essential for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical sectors focused on carbohydrate chemistry and drug discovery.

Application

• Glycosylation Reagent: Acts as a key mannosyl donor in the stereocontrolled synthesis of α-linked oligosaccharides and glycopeptides.
• Pharmaceutical Intermediate: Used in the research and development of carbohydrate-based drugs, including antiviral and anticancer agents.
• Chemical Biology Probe Synthesis: Employed to create labeled glycans or glycomimetics for studying carbohydrate-protein interactions and biological pathways.
• Fine Chemical Synthesis: Serves as a chiral precursor for the preparation of more complex, biologically active molecules and specialty chemicals.
• Academic & Industrial R&D: A fundamental tool for synthetic chemists in universities and corporate R&D centers exploring new glycosylation methodologies.

Basic Information

Product Name	Ethyl 2,3,4,6-Tetra-O-acetyl-α-D-thiomannopyranoside (Contains Up To 20% Beta Isomer)
CAS No.	79389-52-9
Molecular Formula	C₁₆H₂₄O₉S
Molecular Weight	392.42 g/mol
Synonyms	Ethyl 2,3,4,6-Tetra-O-acetyl-1-thio-α-D-mannopyranoside; 1-Thioethyl tetra-O-acetyl-α-D-mannopyranoside; Ethyl 1-thio-α-D-mannopyranoside tetraacetate; α-D-Ethyl thiomannoside tetraacetate; Ethyl tetra-O-acetyl-1-thio-α-D-mannopyranoside; 1-S-Ethyl 2,3,4,6-tetra-O-acetyl-1-thio-α-D-mannopyranoside; Ethyl 2,3,4,6-tetra-O-acetyl-α-D-1-thiomannopyranoside
EINECS	Contact for details

Quality Control

Our Ethyl 2,3,4,6-Tetra-O-acetyl-α-D-thiomannopyranoside is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and optical rotation to confirm identity, isomeric composition, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (α-isomer)
Beta Isomer Content (HPLC)	≤ 20.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.