Description

(2-Iodophenyl)(Morpholino)Methanone is a high-value organic building block featuring a unique combination of an iodophenyl group and a morpholine moiety. This compound is critical for advanced organic synthesis, particularly in the development of complex molecules for pharmaceutical and agrochemical research. It serves as a versatile intermediate for medicinal chemists and process development scientists engaged in cross-coupling reactions and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a building block for advanced polymers and liquid crystals due to its rigid aromatic core and polar morpholine group.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and novel synthetic pathway exploration.

Basic Information

Product Name	(2-Iodophenyl)(Morpholino)Methanone
CAS No.	79271-26-4
Molecular Formula	C11H12INO2
Molecular Weight	317.13 g/mol
Synonyms	2-Iodobenzoyl Morpholine; Morpholin-4-yl-(2-iodophenyl)methanone; (2-Iodobenzoyl)morpholine; 4-(2-Iodobenzoyl)morpholine; 2-Iodo-N-morpholinobenzamide; 79271-26-4; (o-Iodophenyl)(morpholino)methanone
EINECS	Contact for details

Quality Control

Our (2-Iodophenyl)(Morpholino)Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability, consistency, and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.