Description

Benz(A)Anthracene 10,11-Epoxide is a high-purity, polycyclic aromatic hydrocarbon (PAH) epoxide derivative, a critical intermediate in organic synthesis and toxicological research. Its primary value lies in its role as a reactive metabolite model for studying the carcinogenic mechanisms of benz[a]anthracene, a well-known environmental pollutant. This compound is essential for researchers and manufacturers in the fields of analytical chemistry, environmental science, and pharmaceutical development, where precise chemical standards are required for calibration, method development, and mechanistic studies.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the accurate quantification and identification of PAH metabolites in environmental and biological samples via GC-MS or HPLC.
• Toxicology & Cancer Research: Serves as a crucial biochemical tool for investigating the metabolic activation pathways, DNA adduct formation, and mutagenic potential of parent PAHs.
• Organic Synthesis Intermediate: Acts as a key electrophilic building block for the synthesis of more complex derivatives for structure-activity relationship (SAR) studies.
• Environmental Monitoring: Employed in the development and validation of analytical methods to detect and monitor PAH exposure and transformation products in air, water, and soil.
• Biochemical Assay Development: Utilized in enzymatic studies, particularly with epoxide hydrolases, to understand detoxification pathways.
• Pharmaceutical Impurity Profiling: May be used as a standard for assessing impurity levels in APIs where PAH contamination is a concern.

Basic Information

Product Name	Benz(A)Anthracene 10,11-Epoxide
CAS No.	79252-23-6
Molecular Formula	C₁₈H₁₂O
Molecular Weight	244.29 g/mol
Synonyms	10,11-Epoxy-10,11-dihydrobenz[a]anthracene; Benz[a]anthracene 10,11-oxide; BA 10,11-epoxide; 10,11-Dihydrobenz[a]anthracene 10,11-epoxide; Benzanthracene 10,11-epoxide; 1,2-Benzanthracene 10,11-epoxide; 10,11-Epoxybenz[a]anthracene
EINECS	Contact for details

Quality Control

Our Benz(A)Anthracene 10,11-Epoxide is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and analytical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for reference materials, and specifications can be aligned with customer requirements for specific research or compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider storage under inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.