Description

Andrographolide, Deoxy- is a diterpenoid lactone derivative, structurally related to the bioactive natural product andrographolide. This compound is valued for its role as a key intermediate and reference standard in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries for the synthesis of novel therapeutic agents and for analytical purposes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel diterpenoid-based drugs and analogs.
• Biochemical Research: Used as a reference standard and analytical tool in studies investigating structure-activity relationships (SAR) of andrographolide derivatives.
• Natural Product Chemistry: Employed in the semi-synthesis and modification of natural products for enhanced bioactivity or stability.
• Quality Control Standard: Acts as a high-purity certified reference material (CRM) for the identification and assay of related compounds in raw materials and finished products.
• Preclinical Studies: Utilized in in-vitro and in-vivo research to explore potential therapeutic applications, including anti-inflammatory and hepatoprotective activities.

Basic Information

Product Name	Andrographolide, Deoxy-
CAS No.	79233-15-1
Molecular Formula	C₂₀H₃₀O₄
Molecular Weight	334.45 g/mol
Synonyms	14-Deoxyandrographolide; Deoxyandrographolide; 3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; Andrographolide, 14-deoxy-; NSC 330836
EINECS	Contact for details

Quality Control

Our Andrographolide, Deoxy- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets high-grade specifications for research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.