Description

(S)-4,5-Isopropylidene-2-Pentenol CAS NO 79060-23-4 is a high-value chiral building block and intermediate characterized by its stereochemically defined isopropylidene-protected diol moiety. This compound matters for its critical role in the synthesis of complex, optically active molecules, offering chemists precise control over stereochemistry in downstream reactions. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the production of active pharmaceutical ingredients (APIs).

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for constructing complex, stereochemically pure molecules in API development.
• Asymmetric Synthesis Building Block: Used in stereoselective reactions, including nucleophilic additions and cyclizations, to introduce defined chirality.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis (e.g., for hydrogenation or oxidation reactions).
• Natural Product and Fragrance Synthesis: Employed in the total synthesis of natural products and the creation of stereodefined fragrance components.
• Polymer and Material Science Research: Used to introduce chiral centers into specialty monomers for advanced polymeric materials.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(S)-4,5-Isopropylidene-2-Pentenol
CAS No.	79060-23-4
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	(S)-4,5-O-Isopropylidene-2-penten-1-ol; (S)-4,5-O-Isopropylidene-2-pentenol; (S)-2-Penten-1-ol, 4,5-O-(1-methylethylidene)-; (S)-4,5-Isopropylidene-2-penten-1-ol; (S)-4,5-(Isopropylidenedioxy)-2-penten-1-ol; (S)-4,5-Acetonide-2-pentenol
EINECS	Contact for details

Quality Control

Our (S)-4,5-Isopropylidene-2-Pentenol is produced under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and GC analysis. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.