Description

Ormeloxifene CAS NO 78994-24-8 is a selective estrogen receptor modulator (SERM) with a non-steroidal benzopyran structure. This compound is of significant commercial and research interest due to its unique pharmacological profile, distinct from other SERMs like tamoxifen. It is primarily sought after by pharmaceutical research and development organizations, as well as fine chemical suppliers serving the life sciences sector, for use in drug discovery, reference standard preparation, and advanced therapeutic studies.

Application

• Pharmaceutical R&D: Serves as a key active pharmaceutical ingredient (API) intermediate or reference standard in the development of novel therapeutic agents.
• Biomedical Research: Used as a pharmacological tool to study estrogen receptor modulation, bone metabolism, and related endocrine pathways in preclinical models.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the synthesis of specialized drug formulations under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in chemistry, biochemistry, and pharmacology.
• Analytical Standard: Acts as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Ormeloxifene
CAS No.	78994-24-8
Molecular Formula	C24H23NO2
Molecular Weight	357.45 g/mol
Synonyms	Centchroman; 67/20; 1-[2-[[4-[(3S,4R)-7-Methoxy-2,2-dimethyl-3-phenyl-3,4-dihydro-2H-1-benzopyran-4-yl]phenoxy]ethyl]pyrrolidine; Ormeloxifene Hydrochloride (salt form); (3S,4R)-trans-2,2-Dimethyl-3-phenyl-4-[p-(2-pyrrolidin-1-ylethoxy)phenyl]-7-methoxy-2H-1-benzopyran
EINECS	Contact for details

Quality Control

Our Ormeloxifene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.