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trans-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Styrene CAS NO 78782-27-1
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CAS No.:78782-27-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
trans-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Styrene is a high-purity, versatile boronic ester derivative featuring a reactive vinyl group. This compound is a critical advanced pharmaceutical intermediate (API) and a key building block in modern synthetic chemistry, enabling efficient carbon-carbon bond formation. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.
Application
- Suzuki-Miyaura Cross-Coupling Reactions: Serves as a pivotal reagent for introducing styrenyl boronate functionality into target molecules, a fundamental step in drug discovery and development.
- Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas, including oncology and central nervous system (CNS) disorders.
- Agrochemical Synthesis: Acts as a key precursor in creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
- Polymer & Material Science: Employed in the production of specialty polymers, OLED materials, and liquid crystals due to its polymerizable vinyl group.
- Organic Light-Emitting Diodes (OLEDs): Functions as a building block for electron-transport or emissive layer materials in display and lighting technologies.
- Chemical Research & Development: A valuable tool for academic and industrial researchers exploring new synthetic methodologies and creating compound libraries.
Basic Information
| Product Name | trans-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Styrene |
| CAS No. | 78782-27-1 |
| Molecular Formula | C14H19BO2 |
| Molecular Weight | 230.11 g/mol |
| Synonyms | 2-Vinylphenylboronic Acid Pinacol Ester; (2-Ethenylphenyl)boronic Acid Pinacol Ester; trans-2-Vinylbenzeneboronic Acid Pinacol Ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)styrene; 2-Vinylphenylboronic Acid, Pinacol Ester; 2-Ethenylbenzeneboronic Acid Pinacol Ester; B-(2-Vinylphenyl)boronic Acid Pinacol Ester |
| EINECS | Contact for details |
Quality Control
Our trans-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Styrene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistent performance in critical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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