Description

Bis[(Pinacolato)Boryl]Methane CAS NO 78782-17-9 is a versatile organoboron reagent featuring two pinacol-protected boryl groups on a central methylene unit. This compound is a critical building block in modern synthetic chemistry, enabling efficient carbon-carbon and carbon-heteroatom bond formation through Suzuki-Miyaura and other transition-metal-catalyzed cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl motifs prevalent in active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific boron-containing scaffolds.
• Advanced Materials Production: Serves as a monomer or precursor for creating organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Organic Synthesis & Methodology: Enables the introduction of bifunctional boron handles for sequential functionalization in complex molecule assembly.
• Ligand and Catalyst Preparation: Employed in the synthesis of novel bidentate or multidentate ligands for catalysis.
• Chemical Biology & Probe Development: Useful for incorporating stable boron tags into biomolecules for imaging or therapeutic purposes.

Basic Information

Product Name	Bis[(Pinacolato)Boryl]Methane
CAS No.	78782-17-9
Molecular Formula	C17H32B2O4
Molecular Weight	329.06 g/mol
Synonyms	1,1-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane; Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane; Methanediylbis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); Pinacol Methanediboronate; Bis(pinacolatodiboryl)methane; B2Pin2 Methane; B2P2M
EINECS	Contact for details

Quality Control

Our Bis[(Pinacolato)Boryl]Methane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C), HPLC, and GC analysis, to ensure high chemical purity and lot-to-lot consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.