Description

Cyclohexaneacetonitrile, α-Hydroxy-α-Methyl-2-Oxo- is a specialized chiral nitrile building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a hydroxy and an oxo group adjacent to the nitrile functionality, makes it a versatile precursor for constructing complex, stereodefined molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for constructing complex heterocycles and side chains.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic asymmetric reactions.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & R&D Laboratories: A valuable compound for methodological studies in synthetic organic chemistry, exploring new nitrile transformation pathways.

Basic Information

Item	Detail
Product Name	Cyclohexaneacetonitrile, α-Hydroxy-α-Methyl-2-Oxo-
CAS No.	78747-28-1
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	2-(1-Hydroxy-1-methylethyl)-2-oxocyclohexaneacetonitrile; α-Hydroxy-α-methyl-2-oxocyclohexaneacetonitrile; 2-Oxocyclohexaneacetonitrile, α-hydroxy-α-methyl-; (2-Oxocyclohexyl)acetonitrile, α-hydroxy-α-methyl-; 1-Cyano-1-(1-hydroxy-1-methylethyl)cyclohexan-2-one
EINECS	Contact for details

Quality Control

Our production of Cyclohexaneacetonitrile, α-Hydroxy-α-Methyl-2-Oxo- adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.