Description

Tetraisopropyl Difluoromethylenebisphosphonate is a high-purity organophosphorus compound, specifically a fluorinated bisphosphonate ester. This specialty chemical serves as a critical advanced intermediate in the synthesis of complex molecules, valued for its unique difluoromethylene-bridged bisphosphonate structure. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of bisphosphonate-based drugs, including potential treatments for bone disorders.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and plant growth regulators with enhanced activity.
• Ligand and Catalyst Precursor: Serves as a precursor for specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Investigated for incorporation into flame retardants, metal surface treatment agents, and specialty polymers.
• Chemical Biology Probes: Utilized in the development of enzyme inhibitors and molecular probes for biochemical research.
• Process Development: Employed in process chemistry for scaling up the production of fluorinated target molecules.

Basic Information

Product Name	Tetraisopropyl Difluoromethylenebisphosphonate
CAS No.	78715-59-0
Molecular Formula	C13H28F2O6P2
Molecular Weight	380.29 g/mol
Synonyms	Tetraisopropyl (Difluoromethylene)diphosphonate; Difluoromethylenebis(phosphonic acid) tetraisopropyl ester; P,P'-(Difluoromethylene)bis-P,P,P',P'-tetraisopropyl phosphonate; Tetraisopropyl Difluoromethylene Bisphosphonate; Bis(diisopropoxyphosphinyl)difluoromethane; 78715-59-0; (Difluoromethylene)bis[phosphonic acid] tetraisopropyl ester
EINECS	Contact for details

Quality Control

Our Tetraisopropyl Difluoromethylenebisphosphonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.