Description

(1-Ethoxycarbonylmethyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane is a specialized organosilicon reagent featuring a protected amino acid ester functionality. This compound matters as a versatile building block for the controlled synthesis of complex molecules, particularly in pharmaceutical and advanced materials research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel peptide mimetics and silicon-containing scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing silicon-modified amino acid motifs.
• Peptidomimetic Research: Used as a protected glycine equivalent for constructing peptide analogs with enhanced metabolic stability and bioavailability.
• Organosilicon Chemistry: Acts as a precursor for generating reactive silylating agents or for incorporating the 1-aza-2,5-disilacyclopentane ring system into polymers and advanced materials.
• Agrochemical Synthesis: Employed in the development of new generation herbicides and fungicides that utilize silicon to modulate biological activity.
• Ligand and Catalyst Development: Useful for preparing nitrogen-silicon chelating ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, protected bifunctional organosilicon compounds.

Basic Information

Item	Detail
Product Name	(1-Ethoxycarbonylmethyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane
CAS No.	78605-23-9
Molecular Formula	C11H25NO2Si2
Molecular Weight	259.50 g/mol
Synonyms	1-(Ethoxycarbonylmethyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane; N-(Ethoxycarbonylmethyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane; Glycine, N-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentan-1-yl)-, ethyl ester; Azadisilacyclopentane glycine ethyl ester; Ethyl 2-((2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentan-1-yl)methyl)acetate
EINECS	Contact for details

Quality Control

Our (1-Ethoxycarbonylmethyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.