Description

3A,4,7,7A-Tetrahydro-3A-Methyl-2(3H)-Benzofuranone is a versatile lactone derivative with a fused bicyclic structure, serving as a valuable synthetic intermediate in organic chemistry. Its unique molecular framework makes it a critical building block for the synthesis of complex molecules, offering chemists a handle for stereoselective transformations. This compound is particularly relevant for R&D and production in the pharmaceutical and fine chemical sectors, where it is used to construct key pharmacophores and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-inflammatory drugs.
• Fine Chemical Synthesis: Employed in the production of complex fragrances, flavors, and agrochemicals due to its reactive lactone functionality.
• Material Science Research: Used as a monomer or precursor in the development of specialized polymers and resins with tailored properties.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological studies for new organic reactions, including cycloadditions and asymmetric catalysis.

Basic Information

Product Name	3A,4,7,7A-Tetrahydro-3A-Methyl-2(3H)-Benzofuranone
CAS No.	78592-89-9
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	3a-Methyl-3a,4,7,7a-tetrahydro-2-benzofuran-1(3H)-one; 3a-Methyl-3a,4,7,7a-tetrahydroisobenzofuran-1(3H)-one; 3a-Methylhexahydroisobenzofuran-1-one; 3a-Methyl-1-oxo-3a,4,7,7a-tetrahydroisobenzofuran; Tetrahydro-3a-methyl-2(3H)-benzofuranone
EINECS	Contact for details

Quality Control

Our 3A,4,7,7A-Tetrahydro-3A-Methyl-2(3H)-Benzofuranone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, residual solvents, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.