Description

3-(4-Bromophenyl)-3-Chloroacrylonitrile is a versatile halogenated acrylonitrile derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the reactive chloro and cyano groups adjacent to the brominated aromatic ring, enabling diverse functionalization and cyclization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and high-performance resins.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the presence of the bromophenyl group.
• Ligand and Catalyst Development: Useful for constructing complex heterocyclic frameworks and chelating ligands for catalytic systems.
• Chemical Research: A valuable reagent for academic and industrial R&D exploring new reaction methodologies and compound libraries.

Basic Information

Product Name	3-(4-Bromophenyl)-3-Chloroacrylonitrile
CAS No.	78583-87-6
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	3-Chloro-3-(4-bromophenyl)acrylonitrile; (E/Z)-3-(4-Bromophenyl)-3-chloroacrylonitrile; 3-(4-Bromophenyl)-3-chloro-2-propenenitrile; 2-Propenenitrile, 3-(4-bromophenyl)-3-chloro-; 4-Bromo-α-(chloromethylene)benzeneacetonitrile; (4-Bromophenyl)(chloro)methyleneacetonitrile
EINECS	Contact for details

Quality Control

Our 3-(4-Bromophenyl)-3-Chloroacrylonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.