Description

Methyl 4-Fluorobicyclo[2.2.2]Octane-1-Carboxylate is a specialized fluorinated bicyclic ester, a high-value building block in advanced organic synthesis. Its unique, rigid bicyclo[2.2.2]octane scaffold combined with a fluorine substituent makes it a critical intermediate for developing novel compounds with tailored steric and electronic properties. This product is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel drug candidates, especially in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and rigid structure can enhance biological activity and stability.
• Material Science Research: Acts as a monomer or precursor for synthesizing specialty polymers and advanced materials with specific thermal or chemical resistance properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands or metal-organic frameworks (MOFs) for asymmetric catalysis.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the introduction and effects of fluorine in complex molecular architectures.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance molecules, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	Methyl 4-Fluorobicyclo[2.2.2]Octane-1-Carboxylate
CAS No.	78385-85-0
Molecular Formula	C10H15FO2
Molecular Weight	186.22 g/mol
Synonyms	4-Fluorobicyclo[2.2.2]octane-1-carboxylic acid methyl ester; Methyl 4-fluorobicyclo[2.2.2]octane-1-carboxylate; 1-Methoxycarbonyl-4-fluorobicyclo[2.2.2]octane; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-fluoro-, methyl ester; Methyl 4-fluorotricyclo[2.2.2.0]octane-1-carboxylate (common misnomer); 4-Fluoro-1-(methoxycarbonyl)bicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Fluorobicyclo[2.2.2]Octane-1-Carboxylate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency meet the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing specific batch results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Research Grade)
Purity (GC/HPLC)	≥ 98.0% (Premium Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.