Description

Methyl-5-Deoxy-2,3-o-Isopropylidene-D-Ribofuranoside is a high-purity, protected ribofuranoside derivative, a critical chiral building block in organic synthesis. Its value lies in providing a versatile, stereochemically defined scaffold for constructing complex nucleoside analogs and other bioactive molecules. This intermediate is essential for research and development laboratories in the pharmaceutical and biotechnology sectors, particularly for the synthesis of antiviral and anticancer agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used in the development of modified oligonucleotides and probes for genetic and diagnostic studies.
• Carbohydrate Chemistry: Serves as a protected sugar derivative for the synthesis of complex oligosaccharides and glycoconjugates.
• Process Chemistry: Employed in the scalable production of active pharmaceutical ingredients (APIs) requiring a deoxyribose moiety.
• Academic Research: A valuable tool for chemists exploring new synthetic methodologies and structure-activity relationships.

Basic Information

Product Name	Methyl-5-Deoxy-2,3-o-Isopropylidene-D-Ribofuranoside
CAS No.	78341-97-6
Molecular Formula	C10H18O5
Molecular Weight	218.25 g/mol
Synonyms	Methyl 5-Deoxy-2,3-O-isopropylidene-β-D-ribofuranoside; 5-Deoxy-2,3-O-isopropylidene-D-ribofuranose methyl glycoside; Methyl 5-deoxy-2,3-O-(1-methylethylidene)-β-D-ribofuranoside; 1-O-Methyl-5-deoxy-2,3-O-isopropylidene-β-D-ribofuranose; β-D-Ribofuranoside, methyl 5-deoxy-2,3-O-(1-methylethylidene)-; Protected D-ribofuranoside derivative
EINECS	Contact for details

Quality Control

Our Methyl-5-Deoxy-2,3-o-Isopropylidene-D-Ribofuranoside is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, optical rotation, and identity confirmation (IR, NMR). A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.