Description

1H-Pyrrolizine-7-Carboxylic Acid, 2,3,5,6-Tetrahydro-3-Thioxo-, Ethyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding activity.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing and optimizing lead compounds in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Acts as a building block for developing new active ingredients in crop protection agents, such as herbicides or insecticides, with novel modes of action.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals used in electronics, materials science, or as ligands in catalysis.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for fundamental studies in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	1H-Pyrrolizine-7-Carboxylic Acid, 2,3,5,6-Tetrahydro-3-Thioxo-, Ethyl Ester
CAS No.	78312-56-8
Molecular Formula	C10H13NO2S
Molecular Weight	211.28 g/mol
Synonyms	Ethyl 3-Thioxo-2,3,5,6-tetrahydro-1H-pyrrolizine-7-carboxylate; 2,3,5,6-Tetrahydro-3-thioxo-1H-pyrrolizine-7-carboxylic Acid Ethyl Ester; 7-Ethoxycarbonyl-2,3,5,6-tetrahydro-3-thioxo-1H-pyrrolizine; 1H-Pyrrolizine-7-carboxylic acid, 2,3,5,6-tetrahydro-3-thioxo-, ethyl ester; Pyrrolizine-7-carboxylic acid ethyl ester derivative; 3-Thioxopyrrolizine-7-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolizine-7-Carboxylic Acid, 2,3,5,6-Tetrahydro-3-Thioxo-, Ethyl Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.