Description

4,4,4,4',4',4'-Hexafluorovaline,Ethylester is a specialized fluorinated amino acid derivative, identified by CAS NO 78185-92-9. This compound is valued for its unique chemical structure, which introduces fluorine atoms to enhance metabolic stability, lipophilicity, and bioavailability in advanced molecular designs. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, peptide synthesis, and as a key building block for novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of fluorinated peptides and novel drug candidates, particularly for metabolic and central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used to introduce fluorine into lead compounds to modulate their physicochemical properties, such as membrane permeability and metabolic stability.
• Agrochemical Development: Serves as a precursor in creating advanced, fluorinated active ingredients for crop protection products with enhanced efficacy and environmental profiles.
• Peptide Modification: Employed to synthesize non-natural, fluorinated amino acid residues for studying protein structure-function relationships and developing bioactive peptides.
• Bioconjugation & Probe Synthesis: Useful in the development of molecular probes and diagnostic agents where fluorine tags are beneficial for imaging techniques like 19F NMR.
• Material Science Precursor: Potential use in the synthesis of specialized fluorinated polymers or surface-modifying agents.

Basic Information

Product Name	4,4,4,4',4',4'-Hexafluorovaline,Ethylester
CAS No.	78185-92-9
Molecular Formula	C9H11F6NO2
Molecular Weight	279.18 g/mol
Synonyms	Ethyl 2-Amino-3,3,3-trifluoro-2-(trifluoromethyl)propanoate; 2-Amino-3,3,3-trifluoro-2-(trifluoromethyl)propanoic Acid Ethyl Ester; Hexafluorovaline Ethyl Ester; Ethyl Hexafluorovaline; 4,4,4,4',4',4'-Hexafluorovaline Ethyl Ester; F6-Val-OEt; (R/S)-Ethyl 2-amino-3,3,3-trifluoro-2-(trifluoromethyl)propanoate
EINECS	Contact for details

Quality Control

Our 4,4,4,4',4',4'-Hexafluorovaline,Ethylester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.