Description

Phenylglyoxal Monohydrate is a versatile and highly reactive α-ketoaldehyde compound, serving as a critical building block in organic synthesis and biochemical research. Its primary value lies in its ability to selectively modify arginine residues in peptides and proteins, making it an indispensable tool for studying protein structure and function. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries, where it is used to develop novel therapeutics, diagnostic agents, and advanced materials.

Application

• Bioconjugation and Protein Modification: Selective modification of arginine residues in peptides and proteins for structural studies, activity mapping, and the development of bioconjugates.
• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Crosslinking Agent: Used in the preparation of crosslinked polymers, hydrogels, and advanced materials with specific mechanical or chemical properties.
• Fluorescent Probe Synthesis: Building block for creating sensitive fluorescent dyes and probes used in bioimaging and diagnostic assays.
• Enzyme Inhibitor Studies: Tool compound for investigating enzyme mechanisms, particularly those involving arginine in the active site.
• Chemical Biology Research: Fundamental reagent for probing biological pathways and developing chemical tools to understand cellular processes.

Basic Information

Product Name	Phenylglyoxal Monohydrate
CAS No.	78146-52-8
Molecular Formula	C8H6O3 • H2O
Molecular Weight	168.15 g/mol (Anhydrous basis: 150.13 g/mol)
Synonyms	2-Oxo-2-phenylethanal Monohydrate; Phenylethanedial Monohydrate; α-Ketophenylacetaldehyde Monohydrate; Benzoylformaldehyde Monohydrate; Oxophenylacetaldehyde Monohydrate; Phenylglyoxal Hydrate; Glyoxal, Phenyl-, Monohydrate
EINECS	Contact for details

Quality Control

Our Phenylglyoxal Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	9.0 - 11.5%
Melting Point	90 - 95 °C
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.