Description

Ethyl (E)-3-Amino-2-(2-Chloroethanoyl)But-2-Enoate is a high-purity, advanced pharmaceutical intermediate characterized by its specific amino and chloroacetyl functional groups. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting specific enzymatic pathways.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities and reaction methodologies.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptide analogs and mimetics for drug discovery programs.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing specialized fine chemicals for client projects.

Basic Information

Product Name	Ethyl (E)-3-Amino-2-(2-Chloroethanoyl)But-2-Enoate
CAS No.	78120-39-5
Molecular Formula	C8H12ClNO3
Molecular Weight	205.64 g/mol
Synonyms	Ethyl (2E)-3-Amino-2-(2-chloroacetyl)but-2-enoate; (E)-Ethyl 3-Amino-2-(2-chloroacetyl)but-2-enoate; 2-Butenoic acid, 3-amino-2-(2-chloroacetyl)-, ethyl ester, (2E)-; Ethyl 3-Amino-2-(chloroacetyl)crotonate; 78120-39-5; Ethyl 3-Amino-2-(2-chloroethanoyl)but-2-enoate
EINECS	Contact for details

Quality Control

Our Ethyl (E)-3-Amino-2-(2-Chloroethanoyl)But-2-Enoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.