Description

6-Diazo-5-Oxo-L-Norleucylglycine is a specialized diazo compound and modified dipeptide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and biochemical tool for studying enzyme inhibition and protein interactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical probes. Its unique structure makes it valuable for targeted applications in medicinal chemistry and proteomics.

Application

• Biochemical Research: Used as a specialized reagent and intermediate in the study of enzyme mechanisms and metabolic pathways.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex molecules for drug discovery programs.
• Protease Inhibition Studies: Acts as a potential inhibitor or probe for studying protease activity and function.
• Medicinal Chemistry: Employed in the design and synthesis of novel drug candidates targeting specific biological processes.
• Academic Research: Utilized in university and institutional labs for fundamental research in bioorganic chemistry and chemical biology.
• Peptide Mimetic Development: Functions as a core structure for creating peptide mimetics with enhanced stability or activity.

Basic Information

Product Name	6-Diazo-5-Oxo-L-Norleucylglycine
CAS No.	78081-74-0
Molecular Formula	C10H15N5O4
Molecular Weight	269.26 g/mol
Synonyms	DON-Glycine; 6-Diazo-5-oxonorleucylglycine; L-6-Diazo-5-oxonorleucylglycine; Diazooxonorleucylglycine; (2S)-2-[(2-[(2-Amino-2-oxoethyl)amino]-2-oxoethyl)amino]-6-diazo-5-oxohexanoic acid; Glycine, N-[N-[N-(6-diazo-5-oxo-L-norleucyl)]-]; A derivative of 6-Diazo-5-oxo-L-norleucine (DON)
EINECS	Contact for details

Quality Control

Our 6-Diazo-5-Oxo-L-Norleucylglycine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.